interstim2It is estimated that 1 in 6 adults experience some form of bladder control problem.

Particularly challenging is the management of patients with detrusor instability associated with urge incontinence or frequency-urgency syndrome who have failed behavioral modification and pharmocologic therapies. Equally difficult to manage satisfactorily are patients suffering from non-obstructive urinary retention for whom few therapeutic options exist. Until the introduction of sacral neuromodulation, these patients, managed primarily with intermittent or indwelling catheterization, had little hope of regaining volitional voiding function.

The clinical development of the InterStim neurostimulation device represented the first evaluation of such therapy in these target patients.