TheraGenesis

Radio-Oncology

The target of intensity modulated radiotherapy (IMRT) is to irridate the tumor as precisely as possible .... in movable tumor regions this target cannot always be realized very easily. more

Thromboembolic Stroke

It is estimated that 2.2 million people in America and 4.5 million in the European Union have paroxysmal or persistent atrial fibrillation. more

Minimally invasive robotic surgery has become a successful technology associated with reduced trauma, anesthesia, blood loss, risk of infection resulting in faster recovery and return to productive life. more

Left Atrial Appendage Exclusion

Percutaneous epicardial suture closure of the LAA may be performed by tightening pre-tied suture loops around the base of the LAA. more

Cold Plasma Wound Repair

It is well known that cold atmospheric plasmas allow efficient, contact-free and painless treatment without affecting surrounding healthy tissue. more

Colon Cancer

Health screening prophylactic colonoscopic examination of high-risk patients presenting with signs and symptoms characteristic of colonic carcinoma is standard practice in gastroenterology. more

Glaucoma

Many new surgical technologies have developed.... including stent-like devices, surgically implanted within the anterior chamber.... improve aqueous humor outflow and reduce intraocular pressure. more

Thalassemia

Anemia is the characteristic presenting sign of the thalassemias. Treatment begins in pediatric patients and includes chronic blood transfusion, iron chelation, splenectomy and allogeneic hematopoietic transplantation. more

Hepatitis-C

Hyperthermia provides an inovative method for treating patients infected with hepatitis C virus.... postulated to have a direct effect on heat-liable viruses, as well as to stimilate the immune system response to viral infection. more

Cardiogenic Shock

The pLVAD system is as an intra-vascular axial flow pump that withdraws blood from the left ventricle and discharges it in the descending aorta, thus unloading the left ventricle. more

Embolic Protection

Embolic protection system places a sealing balloon proximally, or upstream, to the lesion. The inflated balloon temporarily suspends blood flow so a guidewire can cross the lesion without sending debris into the bloodstream. more

Chronic Total Vascular Occlusions

CTOs are often heavily calcified or extremely fibrotic lesions... The system mechanism is based on reciprocating guidewire advancement causing incremental centralized fractures of the occlusion, thus enabling the advancement of a guidewire. more

Patent Foramen Ovale

The closure device is advanced through the catheter and deployed across the PFO. The aim is to reduce the risk of emboli crossing the PFO and causing serious vascular events such as stroke. more

Septic Shock

Septic shock is an inflammatory state resulting from the systemic response to bacterial infection... Overall mortality in patients with septic shock averages 40%. more

Cardiac Arrest

The goal of therapeutic hypothermia is to reduce brain injury in survivors of cardiac arrest so there is less death and an increased chance of good neurological survival. more

Cerebral Thrombolysis

Ultrasound alters the structure of the thrombus to increase accessibility and dispersion of the drug with a consequent increased dissolution rate and scope. more

Recalcitrant Wounds

Wounds refractory to treatment..... require stimuli to initiate the healing cascade. The study product composed of cell culture media and electrostatically charged particles were identified to stimulate the granulation process in chronic wounds... more

Cryoablation Fibroadenoma

The traditional management options available to women diagnosed with a fibroadenoma include surgical excision. In situ cryoablation has been developed and is less invasive than surgical excision. more

Autologous Cultured Chondrocytes

The product is a cell therapy product used to repair articular cartilage injuries in adults not responded to a prior arthroscopic or surgical repair. The process involves the removal of healthy chondrocytes from the lesioned joint, cell-culture on a scafold and reintroduction over the lesion. more

Chronic Obstructive Pulmonary Disease

A therapeutic fistula in the ilio-femoral region allows blood rich in oxygen to flow from the iliac artery to the iliac vein, thereby increasing the oxygen content of blood returning to the lungs. more

Cryoablation Atrial Fibrillation

The safety and performance of a cryoablation system was evaluated in a long-term, prospective, randomized, multi-center study in patients with medically resistant, symptomatic paroxysmal atrial fibrillation. more

Neurostimulation

Particularly challenging is the management of patients with detrusor instability associated with urge incontinence or frequency-urgency syndrome ...... Equally difficult.... non-obstructive urinary retention.... with sacral neuromodulation, these patients.... regain volitional voiding function. more

Male Urinary Incontinence

A minimally invasive retro-urethral surgical sling implant for the treatment of mild stress urinary incontinence... for men suffering SUI resulting from prostatectomy or TURP and who are not candidates for an artificial urinary sphincter. more

Female Urinary Incontinence

...a hammock-shaped midurethral sling treats SUI by supporting the urethra during times of increased abdominal pressure... its outside-to-in transobturator approach avoids the retropubic space, reducing the potential for serious complications. more

Neonatal Monitoring

Electronic fetal heart rate (FHR) monitoring has evolved into the primary method of intrapartum fetal assessment, not just for high-risk pregnancies, but also for the general population. more

AIDS

Because of the way CJC-1295 is engineered its half life had been extended from 7 minutes to greater than 7 days. Consequently, CJC-1295 injected 1-2 times per week results in elevated levels of Human Growth Hormone and IGF-1. more

Multiple Sclerosis

MRI Studies.... suggest an organic relationship to chronic cerebral hydrostatic pressure changes associated with stenoses of the extracranial venous drainage system..... the potential value of venous angioplasty as a therapeutic measure in the treatment of MS. more

Heart Failure

The concept in cardiac insufficiency involves a modification of the left heart geometry to improve the Frank-Starling characteristics of the myocardium. more

Malignant Glioma

Of patients diagnosed with malignant gliomas, about half are alive 1 year after diagnosis, and 25% after two years.... a novel therapeutic approach: stereotaxic placeent of biodegradable 5-flourouricil microspheres in deeply situated non-operable tumors. more

Point-of-Care IVDs

Empowering clinicians to make decisions at the “point-of-care” has the potential to significantly impact health care delivery and to address the challenges of health disparities. more

Pantothenate Kinase-Associated Neurodegeneration (PKAN)

Movement abnormalities.... involuntary muscle spasms, rigidity, trouble walking... dysarthria.... vision loss.... dementia and psychiatric symptoms... behavioral problems, personality changes, and depression.... more

Schizophrenia

Schizophrenia.... is characterized in.... distortions in form and content of thinking and perception (loosening of associations, delusions, and hallucinations), mood (flattened, inappropriate, or blunted affect) and behavior (bizarre, apparently purposeless and stereotyped activity or inactivity).... more

Dialysis-Dependent Anemia

Patients with renal failure have low levels of erythropoietin which in turn leads to the chronic anemia that accompanies renal failure. The use of recombinant EPO has essentially eliminated anemia as a major cause of morbidity in dialysis patients. more

Heroin Addiction

Based upon the results of this study, the German Parliament implemented a new law in 2009, which permits the administration of Diamorphine in severely addicted patients in controlled settings. It is estimated that some 3.000 patients initially benefited from this new therapeutic approach. more

Myocardial Revascularization

The use of Holmium:YAG laser technology to promote angiogenesis in patients with severe angina pectoris was pioneered by TheraGenesis in studies conducted in Germany, Austria, Spain and Sweden. more

CABG Anastomosis

The developed aortic connector is a mechanical anastomosis device that allows cardiac surgeons to attach saphaneous vein grafts to the aorta without sutures. more

Accomplishments

TheraGenesis staff has contributed to the clinical and regulatory development of a broad range of medical device technologies, pharmaceuticals and biotechnology products. We include a sampling of developmental accomplishments, providing insight into our competence and expertise.

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